Starry Starry Night revolves around a love triangle among Peter Ho, Tammy Chen and Qiu Ze. Tammy Chen coincidentally runs into Peter Ho and both sense that they share a kind of connection. Their love affair lights up after their mobile phones are inadvertently exchanged. Things get increasingly complicated as the viewer discovers that Qiu Ze (playing the step brother of Tammy Chen), has always had a hidden affection for Tammy Chen.
After finding out that Peter Ho is suffering from cancer, he is unwilling to accept that Tammy Chen's happiness should be affected and tries to change her fate.