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The best genital herpes cure is prevention. A wide variety of barrier contraceptives are currently available, with the latex condom most frequently advocated for use in prevention of sexually transmitted infections (STIs). Condoms are now available as both female and male versions, and may be coated with lubricant, spermicide or antiinfective agent.
The latex condom provides a mechanical barrier to infectious agents. The efficacy of the barrier in preventing STIs depends on the permeability of the latex. In their function as a contraceptive, condoms would have to be impermeable to spermatozoa, which are approximately 3000 nm in size. HSV-2 is considerably smaller than spermatozoa, at about 160 nm, and HIV is smaller still at 125 nm.
Electron microscopy of male condoms shows an absence of full-thickness pores, but occasional pits secondary to imperfections in manufacturing. Permeability depends not just on the size of any pores in the latex barrier, but also variables such as the shape of the infectious agent, surface tension, temperature, pressure and pH of the environment.
Sophisticated in vitro models have been developed to determine the permeability of latex condoms to infectious agents.HSVcondomherpesgenital herpespreventionvaccinetr