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Platelet rich plasma therapy or in short PRP therapy is one of the most widely performed treatments for hairfall. It involves the use of concentrated solution of platelets for therapeutic purposes . Platelet rich plasma therapy has been shown to have beneficial effects in reducing the hair fall, increasing hair growth increasing thickness of hair as well as promoting the growth phase of the hair cycle. A number of articles have been put forth in the international journal, providing the benefits of PRP. PRP is not only effective in hair fall but also in a lot of other conditions like skin rejuvenation, wrinkle reduction, as an anitageing therapy, wound management as well as in the treatment of uneven ulcers. The basic procedure is simple, a small quantity of the patients blood is withdrawn and subjected to centrifugation and we get a contacted solution of platelets. These concentrated solution of platelets is injected to the targeted areas of therapeutic purposes. Once the solution is injected to the targeted areas, they tend to disintegrate. On disintegration, they secrete large quantities of natural growth factors. These natural growth factors in stimulation of the stem cells which brings about beneficial affects of PRP. As such there is no specific indication for PRP. It is safe to be used in hypertensives as well as diabetics. but before the start of any procedure it is best to keep the blood sugar as well as the blood pressure levels under control so as to avoid any unforeseen circumstances during the treatment procedures. PRP is used as one of the main treatment modalities for treating non healing diabetic ulcers.