The story begins with a beautiful woman named Karen Maglipot (Jennica Garcia). She is forced by her strict parents to marry Carlos Manansala (Marvin Agustin). Karen does not love Carlos and is searching for her true âÂÂsoulmateâÂÂ. During the wedding, Karen decides to run away from Carlos and her family. Emilene Santos (Chariz Solomon), KarenâÂÂs best friend, runs away with Karen. Karen and Emilene ended up in Batangas where Karen meets Ruben Domingo (Dennis Trillo), a hard Batangas worker. Karen ends up living with him with the goal to find her true soulmate. Meanwhile, KarenâÂÂs sister Joanna (Jolina Magdangal) develops a friendly relationship with Carlos. Then, Karen discovers from a fortune teller named Madame Estelitta (Dinky Doo) that Ruben is KarenâÂÂs soulmate. Will Karen persuade Ruben to be her soulmate? Will Karen ever be found by her strict parents? Will Joanna and Carlos develop a love relationship?